Estrogen Receptor alpha Antikörper

Produktnummer ABIN966095

Der Maus Monoklonal Anti-Estrogen Receptor alpha-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Estrogen Receptor alpha in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Estrogen Receptor alpha Antikörper (ABIN966095)

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 6B6

Produktdetails anti-Estrogen Receptor alpha Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ESR1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Estrogen Receptor alpha Antikörper (ABIN966095)

Saylor: "Beyond informed consent." in: Medical economics, Vol. 87, Issue 4, pp. 25, 30, 32, (2010) (PubMed).

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: ESR1

Hintergrund: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Synonyms: ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ESR1

Molekulargewicht: 66kDa

Gen-ID: 2099

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly