Der Kaninchen Polyklonal Anti-C14orf1-Antikörper wurde für IHC validiert. Er ist geeignet, C14orf1 in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
Kurzübersicht für C14orf1 Antikörper (N-Term) (ABIN966089)
Target
C14orf1
(Chromosome 14 Open Reading Frame 1 (C14orf1))
Reaktivität
Human, Maus
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Dieser C14orf1 Antikörper ist unkonjugiert
Applikation
Immunohistochemistry (IHC)
Bindungsspezifität
N-Term
Aufreinigung
Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse ERG28(Probable ergosterol biosynthetic protein 28)
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Mo, Valachovic, Bard: "The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p)." in: Biochimica et biophysica acta, Vol. 1686, Issue 1-2, pp. 30-6, (2004) (PubMed).
Target
C14orf1
(Chromosome 14 Open Reading Frame 1 (C14orf1))
Andere Bezeichnung
ERG28
Hintergrund
ERG28(Probable ergosterol biosynthetic protein 28) has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. ERG28 may also be responsible for facilitating their interaction. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum. ERG28 interacts with ERG25, ERG26 and ERG27. It also interacts with ERG1, ERG3, ERG5, ERG6 and ERG11.