Der Kaninchen Polyklonal anti-Elf4 Antikörper (ABIN966054) detektiert spezifisch Elf4 in IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ELF4 (ETS-related transcription factor Elf-4)
Elf4
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA, Western blotting: 1µg/ml for 2hrs.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
Elf4
(E74 like ETS transcription factor 4 (Elf4))
Andere Bezeichnung
ELF4
Hintergrund
ELF4 (ETS-related transcription factor Elf-4) is a transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter. ELF4 also transactivates the PRF1 promoter in natural killer (NK) cells. The protein plays a role in the development and function of NK and NK T-cells and in innate immunity. ELF4 interacts via an N-terminal region with the RUNX1 Runt domain and interacts via its C-terminus with PML, this interaction enhances ELF4 transactivation of the bovine lysozyme gene.