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Dvl-B (C-Term) Antikörper

Reaktivität: Freshwater Flatworm (Schmidtea mediterranea) IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN966016
  • Target
    Dvl-B
    Bindungsspezifität
    C-Term
    Reaktivität
    Freshwater Flatworm (Schmidtea mediterranea)
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Unkonjugiert
    Applikation
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Freshwater Flatworms Schmidtea mediterranea Dvl-b (Dishevelled-like protein)
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C
  • Gurley, Rink, Sánchez Alvarado: "Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis." in: Science (New York, N.Y.), Vol. 319, Issue 5861, pp. 323-7, (2008) (PubMed).

  • Target
    Dvl-B
    Hintergrund
    Dvl-b (Dishevelled-like protein) contains PDZ_signaling domain and DEP_dishevelled domain. PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. It may be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-Cterminal). DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway.
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