Dvl-B (C-Term) Antikörper

Produktnummer ABIN966016

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in IHC. Er zeigt eine Reaktivität gegenüber Freshwater Flatworm (Schmidtea mediterranea) und wurde in 1 Publikation erwähnt.

Kurzübersicht für Dvl-B (C-Term) Antikörper (ABIN966016)

Target: Dvl-B

Reaktivität: Freshwater Flatworm (Schmidtea mediterranea)

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Freshwater Flatworms Schmidtea mediterranea Dvl-b (Dishevelled-like protein)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Referenzen

Gurley, Rink, Sánchez Alvarado: "Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis." in: Science (New York, N.Y.), Vol. 319, Issue 5861, pp. 323-7, (2008) (PubMed).

Antigendetails

Target: Dvl-B

Hintergrund: Dvl-b (Dishevelled-like protein) contains PDZ_signaling domain and DEP_dishevelled domain. PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. It may be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-Cterminal). DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway.