KRT8 Antikörper (AA 391-483)
Kurzübersicht für KRT8 Antikörper (AA 391-483) (ABIN965965)
Target
Alle KRT8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 391-483
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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: "Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization." in: Cancer letters, Vol. 265, Issue 2, pp. 188-96, (2008) (PubMed).
: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
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: "Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization." in: Cancer letters, Vol. 265, Issue 2, pp. 188-96, (2008) (PubMed).
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- KRT8 (Keratin 8 (KRT8))
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Andere Bezeichnung
- Cytokeratin 8
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Hintergrund
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Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms: CK8, CYK8, K2C8, KRT8 -
Molekulargewicht
- 54kDa
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Gen-ID
- 3856
Target
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