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Cytokeratin 5 Antikörper

KRT5 Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 1E1 unconjugated
Produktnummer ABIN965962
  • Target Alle Cytokeratin 5 (KRT5) Antikörper anzeigen
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    Reaktivität
    • 120
    • 76
    • 49
    • 12
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 86
    • 44
    • 1
    Maus
    Klonalität
    • 72
    • 59
    Monoklonal
    Konjugat
    • 64
    • 15
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Cytokeratin 5 Antikörper ist unkonjugiert
    Applikation
    • 91
    • 51
    • 46
    • 32
    • 26
    • 22
    • 16
    • 14
    • 13
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.
    Klon
    1E1
    Isotyp
    IgG1
    Top Product
    Discover our top product KRT5 Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Gu, Kim, Ichiki, Park, Nagai, Kitajima: "A usual frameshift and delayed termination codon mutation in keratin 5 causes a novel type of epidermolysis bullosa simplex with migratory circinate erythema." in: The Journal of investigative dermatology, Vol. 121, Issue 3, pp. 482-5, (2003) (PubMed).

  • Target
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    Andere Bezeichnung
    Cytokeratin 5 (KRT5 Produkte)
    Synonyme
    3300001P10Rik antikoerper, AW146334 antikoerper, CK5 antikoerper, K5 antikoerper, Krt2-5 antikoerper, Tfip8 antikoerper, DDD antikoerper, DDD1 antikoerper, EBS2 antikoerper, KRT5A antikoerper, Sak57 antikoerper, ckii antikoerper, wu:fb02h09 antikoerper, wu:fj02d02 antikoerper, wu:fk78b12 antikoerper, zfCKII antikoerper, KRT75 antikoerper, CK-5 antikoerper, Keratin-5 antikoerper, keratin 5 antikoerper, Krt5 antikoerper, KRT5 antikoerper, krt5 antikoerper
    Hintergrund
    Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
    Synonyms: K5, CK5, KRT5A, KRT5
    Molekulargewicht
    62.3kDa
    Gen-ID
    3852
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