Cytokeratin 5 Antikörper

Produktnummer ABIN965961

Dieses Anti-Cytokeratin 5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Cytokeratin 5 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Cytokeratin 5 Antikörper (ABIN965961)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 3E2F1

Produktdetails anti-Cytokeratin 5 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of CK5 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Cytokeratin 5 Antikörper (ABIN965961)

Leibl, Moinfar: "Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation." in: The American journal of surgical pathology, Vol. 30, Issue 4, pp. 450-6, (2006) (PubMed).

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: Cytokeratin 5

Hintergrund: CK5 (keratin 5) is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
Synonyms: K5, DDD, EBS2, KRT5A, KRT5

Gen-ID: 3852