Cytokeratin 7 Antikörper

Produktnummer ABIN965903

Der Maus Monoklonal Anti-Cytokeratin 7-Antikörper wurde für WB, FACS und ELISA validiert. Er ist geeignet, Cytokeratin 7 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für Cytokeratin 7 Antikörper (ABIN965903)

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Klon: 5D12

Produktdetails anti-Cytokeratin 7 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CK7 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Cytokeratin 7 Antikörper (ABIN965903)

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Bouwens: "Cytokeratins and cell differentiation in the pancreas." in: The Journal of pathology, Vol. 184, Issue 3, pp. 234-9, (1998) (PubMed).

Rosenberg, Fuchs, Le Beau, Eddy, Shows: "Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12." in: Cytogenetics and cell genetics, Vol. 57, Issue 1, pp. 33-8, (1991) (PubMed).

Details zu Cytokeratin 7

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Andere Bezeichnung: CK7

Hintergrund: CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants, however, not all variants have been fully described.
Synonyms: KRT7, cytokeratin 7

Molekulargewicht: 51kDa

Gen-ID: 3855