CfPV-2 E7 (N-Term) Antikörper

Produktnummer ABIN965877

Produktdetails

Target: CfPV-2 E7

Bindungsspezifität: N-Term

Reaktivität: Papillomavirus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Dog Canine papillomavirus 2 CfPV-2 E7 protein

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Referenzen

Yuan, Ghim, Newsome, Apolinario, Olcese, Martin, Delius, Felsburg, Jenson, Schlegel: "An epidermotropic canine papillomavirus with malignant potential contains an E5 gene and establishes a unique genus." in: Virology, Vol. 359, Issue 1, pp. 28-36, (2007) (PubMed).

Antigendetails

Target: CfPV-2 E7

Substanzklasse: Viral Protein

Hintergrund: CfPV-2 has unique biological features, it induces papillomas on footpads and interdigital regions which, if infection is persistent, can progress to highly metastatic squamous cell carcinoma. CfPV-2 does not induce oral papillomas in immunocompetent animals and antibodies generated against COPV and CfPV-2 are type-specific. The availability of a new canine papillomavirus with differing genetic and biological properties now makes it possible to study type-specific host immune responses, tissue tropism and the comparative analysis of viral gene functions in the dog.