CD8 Antikörper
Kurzübersicht für CD8 Antikörper (ABIN965817)
Target
Alle CD8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3).
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Aufreinigung
- Antibodies are purified by protein A affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
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Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -20 °C
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: "The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck." in: Cell, Vol. 55, Issue 2, pp. 301-8, (1988) (PubMed).
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: "The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck." in: Cell, Vol. 55, Issue 2, pp. 301-8, (1988) (PubMed).
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- CD8
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Andere Bezeichnung
- CD8
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Hintergrund
- CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
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Gen-ID
- 925
Target
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