CD4 Antikörper

Produktnummer ABIN965795

Der Maus Monoklonal Anti-CD4-Antikörper wurde für FACS und IHC (fro) validiert. Er ist geeignet, CD4 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für CD4 Antikörper (ABIN965795)

Target: CD4

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: B486 (EDU-2)

Produktdetails anti-CD4 Antikörper

Spezifität: This antibody reacts with a 55kD single chain transmembrane glycoprotien, CD4, expressed on T helper lymphocytes, dendritic cells, microglial cells, and cortical thymus cells. Characteristic of CD4 is its four extracellular immunoglobulin-like domains which help it bind to HLA class II molecules when CD4+ T cells interact with antigenpresenting cells or target cells. Another interesting aspect of the CD4 receptor is the fact that it also serves as the primary receptor for the HIV virus. This antibody was clustered at the 2nd International Leucocyte Typing Workshop.

Aufreinigung: Concentrated.

Immunogen: Human leucocytes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1:50-1:100.(Frozen sections only)
Flow cytometry: 1:150-1:300.
Staining Procedure: This antibody can be used on frozen sections only. The antibody may be used at a dilution of 1:50-1:100 in IHC. The optimal conditions should be determined by the individual laboratory.

Kommentare:

Recommended Positive Control: Tonsil, Thymus, Spleen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/ml.

Buffer: 20 mM tris-borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing fetal bovine serum, BMC-6 carrier polysaccharides, carrier protein, pH 7.5

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-CD4 Antikörper (ABIN965795)

Zosimova: "[Gas chromatographic detection of benzene, toluene and xylene in biological matter]." in: Sudebno-meditsinskaia ekspertiza, Vol. 29, Issue 3, pp. 37-8, (1986) (PubMed).

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Gen-ID: 920

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events