CD4 Antikörper
Kurzübersicht für CD4 Antikörper (ABIN965794)
Target
Alle CD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified recombinant human CD4 expressed in E. Coli strain BL21 (DE3).
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Aufreinigung
- Antibodies are purified by protein A affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
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Western Blot, IHC and ELISA. Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -20 °C
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: "Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).
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: "Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).
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- CD4
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Andere Bezeichnung
- CD4
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Hintergrund
- The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells
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Gen-ID
- 920
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Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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