CD19 Antikörper
Kurzübersicht für CD19 Antikörper (ABIN965770)
Target
Alle CD19 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified recombinant human CD19 expressed in E. Coli strain M15.
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Aufreinigung
- Antibodies are purified by protein A affinity chromatography
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Isotyp
- IgG2a
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Applikationshinweise
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Western Blot: Dilution 1: 2000- 5,000
IHC(P): Dilution 1: 100- 1: 400
IHC(F): Dilution 1: 200- 1: 400
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -20 °C
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: "Inhibition, by vinca alkaloids and colchicine, of antigenic modulation induced by anti-CD19 monoclonal antibodies." in: Leukemia research, Vol. 12, Issue 2, pp. 135-41, (1988) (PubMed).
: "Evaluation of a method of production and purification of monoclonal antibodies for clinical applications." in: Journal of immunological methods, Vol. 102, Issue 2, pp. 187-93, (1987) (PubMed).
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: "Inhibition, by vinca alkaloids and colchicine, of antigenic modulation induced by anti-CD19 monoclonal antibodies." in: Leukemia research, Vol. 12, Issue 2, pp. 135-41, (1988) (PubMed).
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- CD19 (CD19 Molecule (CD19))
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Andere Bezeichnung
- CD19
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Hintergrund
- The CD19 antigen (95kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.
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Gen-ID
- 930
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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