BNP Antikörper

Produktnummer ABIN965691

Dieses Anti-BNP-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BNP in IHC und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BNP Antikörper (ABIN965691)

Target: BNP (Brain Natriuretic Peptide (BNP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BNP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 3A6F7C7

Produktdetails anti-BNP Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP, conjugated to KLH.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-BNP Antikörper (ABIN965691)

Pfister, Erdmann, Schneider: "[Natriuretic peptides BNP and NT-pro-BNP--the "new troponins" for estimation of heart failure?]." in: Deutsche medizinische Wochenschrift (1946), Vol. 128, Issue 18, pp. 1007-12, (2003) (PubMed).

Details zu BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Andere Bezeichnung: BNP

Hintergrund: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.
Synonyms: BNP, NPPB

Gen-ID: 4879

Pathways: Hormone Activity