BLK Antikörper
(1 reference)Kurzübersicht für BLK Antikörper (ABIN965674)
Target
Alle BLK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3)
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Aufreinigung
- Crude ascites.
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Isotyp
- IgG1
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anti-B Lymphoid Tyrosine Kinase (BLK) (AA 241-494) antibody
BLK Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) antibodyBLK Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 7A12 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-30), (N-Term) antibodyBLK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03107 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 1E6 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3E5-3A8 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9D10B7 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibodyBLK Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 9D10D1 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibodyBLK Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- -20 °C
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: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
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: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
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- BLK (B Lymphoid Tyrosine Kinase (BLK))
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Andere Bezeichnung
- BLK
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Hintergrund
- BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src nonreceptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
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Gen-ID
- 640
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Pathways
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Target
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