Apolipoprotein M Antikörper

Produktnummer ABIN965579

Der Monoklonal Anti-Apolipoprotein M-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, Apolipoprotein M in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für Apolipoprotein M Antikörper (ABIN965579)

Target: Apolipoprotein M (APOM)

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser Apolipoprotein M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Apolipoprotein M Antikörper

Spezifität: Ni-NTA purified full-length recombinant ApoM.trx expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Antibodies are purified by protein A affinity chromatography

Isotyp: IgG1, IgG2b

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500- 1: 2,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Referenzen für anti-Apolipoprotein M Antikörper (ABIN965579)

Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).

Duan, Dahlbäck, Villoutreix: "Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis." in: FEBS letters, Vol. 499, Issue 1-2, pp. 127-32, (2001) (PubMed).

Xu, Dahlbäck: "A novel human apolipoprotein (apoM)." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, (1999) (PubMed).

Details zu Apolipoprotein M

Target: Apolipoprotein M (APOM)

Andere Bezeichnung: ApoM

Hintergrund: ApoM(apolipoprotein M,also designated G3a or NG20),with 188-amino acid protein(about 21kDa),is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro,Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment.Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs,and also found in triglyceride-rich lipoproteins and LDLs.

Gen-ID: 55937