Apolipoprotein M Antikörper

Produktnummer ABIN965578

Dieses Monoklonal-Antikörper erkennt spezifisch Apolipoprotein M in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Apolipoprotein M Antikörper (ABIN965578)

Target: Apolipoprotein M (APOM)

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser Apolipoprotein M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Apolipoprotein M Antikörper

Spezifität: TRX purified full length recombinant ApoM-GST expressed in E. Coli strain BL21 (DE3).

Aufreinigung: Antibodies are purified by protein A affinity chromatography

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500- 1: 1,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Referenzen für anti-Apolipoprotein M Antikörper (ABIN965578)

Wolfrum, Poy, Stoffel: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." in: Nature medicine, Vol. 11, Issue 4, pp. 418-22, (2005) (PubMed).

Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).

Xu, Dahlbäck: "A novel human apolipoprotein (apoM)." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, (1999) (PubMed).

Details zu Apolipoprotein M

Target: Apolipoprotein M (APOM)

Andere Bezeichnung: ApoM

Hintergrund: Apolipoprotein M (ApoM) is a member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. It is positively related to leptin. It is mainly expressed in liver and kidney. ApoM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions.

Gen-ID: 55937