Apoa5(bd) Antikörper

Produktnummer ABIN965572

Dieser Monoklonal Antikörper detektiert spezifisch Apoa5(bd) in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Apoa5(bd) Antikörper (ABIN965572)

Target: Apoa5(bd)

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Spezifität: Ni-NTA purified truncated recombinant human APOA5 expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Crude ascites.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Antigendetails

Target: Apoa5(bd)

Hintergrund: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

Gen-ID: 116519