Actin, gamma 1 Antikörper (C-Term)

Produktnummer ABIN965509

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Actin, gamma 1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Actin, gamma 1 Antikörper (C-Term) (ABIN965509)

Target: Actin, gamma 1 (ACTG1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Actin, gamma 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Actin, gamma 1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Actin, cytoplasmic 2 (ACTG1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human Actin , identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Referenzen für anti-Actin, gamma 1 Antikörper (ABIN965509)

Goebel, Brockmann, Bönnemann, Warlo, Hanefeld, Labeit, Durling, Laing: "Actin-related myopathy without any missense mutation in the ACTA1 gene." in: Journal of child neurology, Vol. 19, Issue 2, pp. 149-53, (2004) (PubMed).

Laing, Clarke, Dye, Liyanage, Walker, Kobayashi, Shimakawa, Hagiwara, Ouvrier, Sparrow, Nishino, North, Nonaka: "Actin mutations are one cause of congenital fibre type disproportion." in: Annals of neurology, Vol. 56, Issue 5, pp. 689-94, (2004) (PubMed).

Gunning, Ponte, Okayama, Engel, Blau, Kedes et al.: "Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently ..." in: Molecular and cellular biology, Vol. 3, Issue 5, pp. 787-95, (1983) (PubMed).

Details zu Actin, gamma 1

Target: Actin, gamma 1 (ACTG1)

Andere Bezeichnung: Actin, cytoplasmic 2

Hintergrund: Actin, a highly conserved protein, is a major component of both the cytoskeletal and contractile structures in the cell types. It varies in amount, being related to the type of differentiation and to the functional state of cells and tissues. The actins exhibit over 90 % sequence homology, but each isoform has a unique NH2-terminal sequence. The isoforms are comprised of three alpha-actin, one beta-actin, two gamma-actin. Because the amino acid sequence of the C-terminal is the same for almost all actins, this antibody has been raised using a synthetic peptide corresponding to the C-terminal 11 residues.

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization