PRDM1 Antikörper (C-Term)

Produktnummer ABIN964913

Hersteller Produkt- Nr.: 600-401-b52

Der Kaninchen Polyklonal Anti-PRDM1-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet, PRDM1 in Proben von Human zu detektieren.

Kurzübersicht für PRDM1 Antikörper (C-Term) (ABIN964913)

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-PRDM1 Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 600-401-b52

Hersteller: Rockland

Verwendungszweck: PRDM1 BLIMP1 Antibody

Kreuzreaktivität (Details): This affinity purified antibody is directed against human BLIMP1 protein.

Produktmerkmale: Synonyms: rabbit anti-Blimp-1 antibody, rabbit anti-PRDM-1 antibody, anti-PRDM1/BLIMP1 antibody, PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Beta-lymphocyte-induced maturation protein 1, positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, BLIMP1, BLIMP 1, PRDM1

Aufreinigung: The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: Anti-Blimp1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminus of human, mouse, and rat PRDM1/BLIMP1.

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 5 μg/mL

Application Note: This affinity purified antibody has been tested for use in ELISA, Immunohistochemistry, and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~88 kDa in size corresponding to BLIMP1 by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1,000

Immunoprecipitation Dilution: 5-10 μg/mL

ELISA Dilution: 1:20,000 - 1:40,000

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.15 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store Blimp1 antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Andere Bezeichnung: PRDM1

Hintergrund: Background: Anti-Blimp1 is ideal for Immunology, Epigenetic and Nuclear Signaling research. PRDM1/Blimp1 (PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-binding factor 1, or PRDI-BF1, or Beta-lymphocyte-induced maturation protein 1) is one of several transcription factors which drives the maturation of B-lymphocytes into Ig secreting cells. In the nucleus, PRDM1/BLIMP1 functions as a transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Transcription of the PRDM1 gene is increased upon virus induction. PRDM1/Blimp1 also interacts with PRMT5. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Gen-ID: 639, 25008939

UniProt: Q60636

Pathways: Regulation of Muscle Cell Differentiation