CDNF Antikörper
Kurzübersicht für CDNF Antikörper (ABIN956414)
Target
Alle CDNF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Human, CDNF protein
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Aufreinigung
- CDNF-affinity purified
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Immunogen
- Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant.
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Isotyp
- IgG
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Applikationshinweise
- Westernimmunoblotting, recommended dilution 1:6 000 to 1:10 000, ELISA: 1:125 000
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Kommentare
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Synonym: ARMETL1
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/ml
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Buffer
- Concentrated ammonium sulphide in PBS pH 7.4
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Handhabung
- As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- This product is shipped in non-frozen liquid form in ambient conditions
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- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
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Andere Bezeichnung
- CDNF
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Hintergrund
- CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta
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UniProt
- Q49AH0
Target
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