Xanthine Dehydrogenase (XDH) (AA 213-242), (N-Term) Antikörper

Details zu Produkt Nr. ABIN955594, Anbieter: Anmelden zum Anzeigen
Antigen
  • XO
  • XOR
  • Xor
  • Xox-1
  • Xox1
  • XDH
  • im:7146167
  • DDBDRAFT_0219626
  • DDBDRAFT_0230176
  • DDB_0219626
  • DDB_0230176
  • xanthine dehydrogenase
  • xanthine dehydrogenase/oxidase
  • Xanthine dehydrogenase
  • XDH
  • Xdh
  • xdh
  • LOC576712
  • Trebr_1754
Epitop
AA 213-242, N-Term
11
9
7
2
2
2
1
1
Reaktivität
Human, Maus
53
41
34
28
2
2
2
2
2
1
1
1
Wirt
Kaninchen
87
3
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
9
7
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
75
40
35
24
19
13
11
8
7
6
4
3
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide between 213~242 amino acids from the N-terminal region of human XDH
Isotyp Ig Fraction
Spezifität This antibody detects Xanthine dehydrogenase/oxidase (N-term).
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse.
Reinigung Protein A column followed by peptide affinity purification
Antigen
Andere Bezeichnung XDH (XDH Antibody Abstract)
Hintergrund XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.Synonyms: Xanthine dehydrogenase/oxidase
Gen-ID 7498
NCBI Accession NP_000370
Pathways Positive Regulation of Endopeptidase Activity
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Xanthine Dehydrogenase (XDH) (AA 213-242), (N-Term) antibody (ABIN955594) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with XDH Antibody ...
Western Blotting (WB) image for anti-Xanthine Dehydrogenase (XDH) (AA 213-242), (N-Term) antibody (ABIN955594) Western blot analysis of XDH Antibody (N-term) in mouse lung tissue lysates (35 µg/la...
Produkt verwendet in: Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, 2009 (PubMed).

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