XDH Antikörper (N-Term)
Kurzübersicht für XDH Antikörper (N-Term) (ABIN955594)
Target
Alle XDH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 213-242, N-Term
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Spezifität
- This antibody detects Xanthine dehydrogenase/oxidase (N-term).
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse.
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Aufreinigung
- Protein A column followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 213~242 amino acids from the N-terminal region of human XDH
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).
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- XDH (Xanthine Dehydrogenase (XDH))
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Andere Bezeichnung
- XDH
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Hintergrund
- XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.Synonyms: Xanthine dehydrogenase/oxidase
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Gen-ID
- 7498
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NCBI Accession
- NP_000370
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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