Zitiert in 1 Publikation.
Dieser Anti-UPK1A-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von UPK1A in WB und EIA. Geeignet für Human.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Feenstra, Thøgersen, Wieser, Peschel, Ball, Brandes, Satchell, Stockner, Aarestrup, Rees, Kain: "Adhesion of Escherichia coli under flow conditions reveals potential novel effects of FimH mutations." in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Vol. 36, Issue 3, pp. 467-478, (2017) (PubMed).
Target
UPK1A
(Uroplakin 1a (UPK1A))
Andere Bezeichnung
Uroplakin-1a (UPK1A)
Hintergrund
The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.Synonyms: TSPAN21, Tetraspanin-21, Tspan-21, UP1a, UPIa, UPKa, Uroplakin Ia