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Tyrosine Hydroxylase Antikörper

Der Huhn Polyklonal anti-Tyrosine Hydroxylase Antikörper wird verwendet zum Nachweis von Tyrosine Hydroxylase in Proben von Human und Maus. Er wurde validiert für WB, IF und IHC (p).
Produktnummer ABIN955409
1.073,85 €
Zzgl. Versandkosten 20,00 € und MwSt
0.2 mg
Lieferung nach: Deutschland
Lieferung in 16 Werktagen

Kurzübersicht für Tyrosine Hydroxylase Antikörper (ABIN955409)

Target

Alle Tyrosine Hydroxylase (TH) Antikörper anzeigen
Tyrosine Hydroxylase (TH)

Reaktivität

  • 143
  • 138
  • 115
  • 11
  • 9
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 141
  • 35
  • 7
  • 4
  • 2
Huhn

Klonalität

  • 125
  • 64
Polyklonal

Konjugat

  • 116
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation

  • 138
  • 101
  • 58
  • 55
  • 35
  • 28
  • 22
  • 21
  • 16
  • 14
  • 13
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Spezifität

    Recognizes Tyrosine Hydroxylase (TYH).

    Aufreinigung

    Affinity Chromatography using a peptide column.

    Immunogen

    Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (P24529) and Human (P07101) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.2 mg/mL

    Buffer

    10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted in the dark at 2-8 °C.
  • Target

    Tyrosine Hydroxylase (TH)

    Andere Bezeichnung

    Tyrosine 3-Monooxygenase (TH)

    Hintergrund

    Human TYH (EC 1.14.16.2) is a 58,523 dalton protein (528 amino acids) responsible for the enzymatic conversion of L-tyrosine to L-DOPA (dihydroxyphenylalanine). This enzyme is expressed in all catecholaminergic neurons of the CNS and PNS. In the CNS, TYH-positive neurons can be found within the substantia nigra, ventral tegmental area, locus ceruleus, and hypothalamus. In the PNS, TYH-positive neurons can be found within the sympathetic chain, pre-vertebral ganglia and the adrenal medulla.Synonyms: TYH, Tyrosine 3-hydroxylase

    Gen-ID

    7054

    NCBI Accession

    NP_000351

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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