TPSD1 Antikörper (C-Term)

Produktnummer ABIN955305

Dieses Anti-TPSD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TPSD1 in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für TPSD1 Antikörper (C-Term) (ABIN955305)

Target: TPSD1 (Tryptase delta 1 (TPSD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPSD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-TPSD1 Antikörper

Bindungsspezifität: AA 171-201, C-Term

Spezifität: This antibody detects TPSD1 (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 171-201 amino acids from the C-terminal region of human TPSD1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu TPSD1

Target: TPSD1 (Tryptase delta 1 (TPSD1))

Andere Bezeichnung: TPSD1

Hintergrund: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.Synonyms: Tryptase delta

Gen-ID: 23430

NCBI Accession: NP_036349