Der Kaninchen Polyklonal anti-TNK2 Antikörper wird verwendet zum Nachweis von TNK2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC (p) und EIA.
TNK2
Reaktivität: Human
DB
Wirt: Kaninchen
Polyclonal
RB15592
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
TNK2
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Andere Bezeichnung
TNK2 / ACK1
Hintergrund
ACK encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation pathway.Synonyms: Activated CDC42 kinase 1