THO Complex 4 Antikörper (Middle Region)

Produktnummer ABIN955189

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch THO Complex 4 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für THO Complex 4 Antikörper (Middle Region) (ABIN955189)

Target: THO Complex 4 (THOC4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THO Complex 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-THO Complex 4 Antikörper

Bindungsspezifität: AA 59-89, Middle Region

Spezifität: This antibody detects THOC4 / ALY (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 59-89 amino acids from the Central region of human THOC4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Referenzen für anti-THO Complex 4 Antikörper (ABIN955189)

Souki, Sandri-Goldin: "Arginine methylation of the ICP27 RGG box regulates the functional interactions of ICP27 with SRPK1 and Aly/REF during herpes simplex virus 1 infection." in: Journal of virology, Vol. 83, Issue 17, pp. 8970-5, (2009) (PubMed).

Johnson, Li, Sandri-Goldin: "The cellular RNA export receptor TAP/NXF1 is required for ICP27-mediated export of herpes simplex virus 1 RNA, but the TREX complex adaptor protein Aly/REF appears to be dispensable." in: Journal of virology, Vol. 83, Issue 13, pp. 6335-46, (2009) (PubMed).

Details zu THO Complex 4

Target: THO Complex 4 (THOC4)

Andere Bezeichnung: THOC4 / ALY

Hintergrund: THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.Synonyms: Ally of AML-1 and LEF-1, BEF, THO complex subunit 4, THO4, Transcriptional coactivator Aly/REF, bZIP-enhancing factor BEF

Gen-ID: 10189

NCBI Accession: NP_005773