SYT1 Antikörper

Produktnummer ABIN955025

Der Huhn-Polyklonal Anti-SYT1-Antikörper wurde für WB, IHC (p) und IF validiert. Er ist geeignet zum Nachweis von SYT1 in Proben aus Human und Maus. }

Kurzübersicht für SYT1 Antikörper (ABIN955025)

Target: SYT1 (Synaptotagmin I (SYT1))

Reaktivität: Human, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser SYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-SYT1 Antikörper

Spezifität: Recognizes Synaptotagmin-1.

Aufreinigung: Affinity Chromatography using a peptide column.

Immunogen: Four different antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_033332) and Human (NP_005630) gene products. Production: After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.4 mg/ml. Finally, equal volumes of each of the four affinity-purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized. Antibodies were affinity-purified and mixed in equal concentrations.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.4 mg/mL

Buffer: 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted in the dark at 2-8 °C.

Details zu SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Andere Bezeichnung: Synaptotagmin-1

Hintergrund: Human Synaptotagmin-1 is a 47,442 dalton protein (422 amino acids) associated with pre-synaptic terminals of the PNS and CNS. Synaptotagmin-1 binds calcium and initiates the fusion of vesicles with the pre-synaptic membrane. This protein is also believed to be the target of proteolytic activity associated with Botulinum neurotoxin A.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65

Gen-ID: 6857

NCBI Accession: NP_001129277

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport