SPG20 Antikörper (C-Term)

Produktnummer ABIN954907

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPG20 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPG20 Antikörper (C-Term) (ABIN954907)

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SPG20 Antikörper

Bindungsspezifität: AA 490-519, C-Term

Spezifität: This antibody recognizes Human

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 490-519 amino acids from the C-terminal region of Human SPG20 Genename: SPG20

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Details zu SPG20

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Andere Bezeichnung: Spartin / SPG20

Hintergrund: SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome)Synonyms: KIAA0610, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1

Molekulargewicht: 72833 Da

Gen-ID: 23111

NCBI Accession: NP_001135766

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interaktom