SORD Antikörper (Middle Region)

Produktnummer ABIN954884

Der Kaninchen Polyklonal Anti-SORD-Antikörper wurde für WB und EIA validiert. Er ist geeignet, SORD in Proben von Human zu detektieren.

Kurzübersicht für SORD Antikörper (Middle Region) (ABIN954884)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SORD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SORD Antikörper

Bindungsspezifität: AA 210-239, Middle Region

Spezifität: This antibody recognizes Human SORD (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of Human SORD. Genename: SORD

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: SORD

Hintergrund: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor. Synonyms: L-iditol 2-dehydrogenase, Sorbitol dehydrogenase

Molekulargewicht: 38325 Da

Gen-ID: 6652

NCBI Accession: NP_003095