Snurportin 1 Antikörper (Middle Region)
Kurzübersicht für Snurportin 1 Antikörper (Middle Region) (ABIN954877)
Target
Alle Snurportin 1 (SNUPN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 199-228, Middle Region
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Spezifität
- This antibody detects Snurportin-1 (SNUPN).
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Purified through a protein A column; followed by peptide affinity purification.
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the central region ( between 199-228aa) of human Snurportin-1 (SNUPN).
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Snurportin 1 (SNUPN)
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Andere Bezeichnung
- Snurportin-1 (SNUPN)
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Hintergrund
- The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.Synonyms: KPNBL, RNA U transporter 1, RNUT1, SPN1, Snurportin1
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Gen-ID
- 10073
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NCBI Accession
- NP_001036046
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus
Target
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