Der Kaninchen Polyklonal Anti-SH2D4B-Antikörper wurde für WB, IF, IHC (p) und EIA validiert. Er ist geeignet, SH2D4B in Proben von Human zu detektieren.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
SH2D4B
(SH2 Domain Containing 4B (SH2D4B))
Andere Bezeichnung
SH2D4B
Hintergrund
SH2D4B (SH2 domain containing 4B) is a 431 amino acid protein that contains one SH2 domain, exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 10q23.1. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.Synonyms: SH2 domain-containing protein 4B