SH2D4A Antikörper (N-Term)

Produktnummer ABIN954787

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SH2D4A in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für SH2D4A Antikörper (N-Term) (ABIN954787)

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH2D4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-SH2D4A Antikörper

Bindungsspezifität: AA 45-75, N-Term

Spezifität: Recognizes SH2D4A (N-term).

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 45-75 amino acids from the N-terminal region of Human SH2D4A Genename: SH2D4A

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-SH2D4A Antikörper (ABIN954787)

Lapinski, Oliver, Kamen, Hughes, Saunders, King: "Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 2019-27, (2008) (PubMed).

Details zu SH2D4A

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Andere Bezeichnung: SH2D4A

Hintergrund: SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.Synonyms: Protein SH(2)A, SH2 domain-containing protein 4A, SH2A

Gen-ID: 63898

NCBI Accession: NP_001167630