SRGN Antikörper (C-Term)

Produktnummer ABIN954731

Der Kaninchen Polyklonal anti-SRGN Antikörper wird verwendet zum Nachweis von SRGN in Proben von Human. Er wurde validiert für WB, EIA und FACS.

Kurzübersicht für SRGN Antikörper (C-Term) (ABIN954731)

Target: SRGN (serglycin (SRGN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRGN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Flow Cytometry (FACS)

Produktdetails anti-SRGN Antikörper

Bindungsspezifität: AA 118-148, C-Term

Spezifität: This antibody recognizes Serglycin at c-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 118-148aa) of human Serglycin.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SRGN

Target: SRGN (serglycin (SRGN))

Andere Bezeichnung: Serglycin / PRG1

Hintergrund: The SRGN gene encodes serglycin, a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.Synonyms: Hematopoetic proteoglycan core protein, Platelet proteoglycan core protein, SRGN, Secretory granule proteoglycan core protein

Gen-ID: 5552

NCBI Accession: NP_002718

Pathways: Maintenance of Protein Location