Septin 5 Antikörper (N-Term)

Produktnummer ABIN954727

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Septin 5 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Septin 5 Antikörper (N-Term) (ABIN954727)

Target: Septin 5 (SEPT5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Septin 5 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Spezifität: Recognizes SEPT5 (N-term).

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human SEPT5 Genename: SEPT5

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: Septin-5 (SEPT5)

Hintergrund: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq].Synonyms: CDCrel-1, Cell division control-related protein 1, PNUTL1, Peanut-like protein 1

Gen-ID: 5413

NCBI Accession: NP_002679

Pathways: Synaptic Vesicle Exocytosis