BSCL2 Antikörper (N-Term)

Produktnummer ABIN954710

Produktdetails anti-BSCL2 Antikörper

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Bindungsspezifität: AA 85-115, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BSCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Seipin.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 85-115 amino acids from the N-terminal region of human BSCL2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Andere Bezeichnung: Seipin / BSCL2 (BSCL2 Produkte)

Synonyme: GNG3LG antikoerper, HMN5 antikoerper, SPG17 antikoerper, 2900097C17Rik antikoerper, AI046355 antikoerper, Gng3lg antikoerper, BSCL2, seipin lipid droplet biogenesis associated antikoerper, Berardinelli-Seip congenital lipodystrophy 2 (seipin) antikoerper, BSCL2 antikoerper, Bscl2 antikoerper

Hintergrund: This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this geneSynonyms: Bernardinelli-Seip congenital lipodystrophy type 2 protein

Gen-ID: 26580

NCBI Accession: NP_001116427