RPL7 Antikörper (N-Term)

Produktnummer ABIN954601

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RPL7 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RPL7 Antikörper (N-Term) (ABIN954601)

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-RPL7 Antikörper

Bindungsspezifität: AA 5-35, N-Term

Spezifität: Recognizes RPL7 (N-term).

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of Human RPL7 Genename: RPL7

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Andere Bezeichnung: RPL7

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.Synonyms: 60S ribosomal protein L7

Gen-ID: 6129

NCBI Accession: NP_000962