RNH1 Antikörper (C-Term)

Produktnummer ABIN954547

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNH1 in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RNH1 Antikörper (C-Term) (ABIN954547)

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-RNH1 Antikörper

Bindungsspezifität: AA 424-454, C-Term

Spezifität: This antibody reaccts to RNH1.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 424-454 amino acids from the C-terminal region of human RNH1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RNH1

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Andere Bezeichnung: Ribonuclease Inhibitor (RNH1)

Hintergrund: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.Synonyms: PRI, Placental ribonuclease inhibitor, RAI, RNH, Ribonuclease/angiogenin inhibitor 1

Molekulargewicht: 49973 Da

Gen-ID: 6050

NCBI Accession: NP_002930