PC Antikörper (N-Term)

Produktnummer ABIN954396

Dieses Anti-PC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PC in WB, IHC (p) und EIA. Geeignet für Human und Maus.

Kurzübersicht für PC Antikörper (N-Term) (ABIN954396)

Target: PC (Pyruvate Carboxylase (PC))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PC Antikörper

Bindungsspezifität: AA 52-82, N-Term

Spezifität: This antibody reacts to PC.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PC

Target: PC (Pyruvate Carboxylase (PC))

Andere Bezeichnung: Pyruvic Carboxylase (PC)

Hintergrund: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].Synonyms: PCB, Pyruvate carboxylase mitochondrial

Gen-ID: 5091

NCBI Accession: NP_000911