PSTPIP1 Antikörper (N-Term)

Produktnummer ABIN954360

Dieses Anti-PSTPIP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PSTPIP1 in WB und EIA. Geeignet für Human.

Kurzübersicht für PSTPIP1 Antikörper (N-Term) (ABIN954360)

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSTPIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PSTPIP1 Antikörper

Bindungsspezifität: AA 88-118, N-Term

Spezifität: This antibody recognizes Human PSTPIP1 / CD2BP1 (N-term).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of Human PSTPIP1 / CD28P1 Genename: PSTPIP1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PSTPIP1

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Andere Bezeichnung: PSTPIP1 / CD2BP1

Hintergrund: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.Synonyms: CD2 antigen-binding protein 1, CD2 cytoplasmic tail-binding protein, CD2-binding protein 1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PEST phosphatase-interacting protein 1, PSTPIP, Proline-serine-threonine phosphatase-interacting protein 1

Molekulargewicht: 47591 Da

Gen-ID: 9051

NCBI Accession: NP_003969