PRUNE Antikörper

Produktnummer ABIN954343

Produktdetails anti-PRUNE Antikörper

Target: PRUNE (Prune Exopolyphosphatase (PRUNE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRUNE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes PRUNE

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography

Immunogen: Recombinant protein.

Klon: 1C11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PRUNE

Target: PRUNE (Prune Exopolyphosphatase (PRUNE))

Andere Bezeichnung: PRUNE (PRUNE Produkte)

Hintergrund: PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune, h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.Synonyms: DRES-17, DRES17, Drosophila-related expressed sequence 17, HTcD37, Protein prune homolog, hPrune

Gen-ID: 58497

NCBI Accession: NP_067045

UniProt: Q86TP1