PROC Antikörper

Produktnummer ABIN954315

Der Maus Monoklonal anti-PROC Antikörper (Klon CaC-11) (ABIN954315) detektiert spezifisch PROC in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PROC Antikörper (ABIN954315)

Target: PROC (Vitamin K-dependent protein C (PROC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PROC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: CaC-11

Produktdetails anti-PROC Antikörper

Spezifität: This antibody is specific for Human Protein C/APC in the presence of 5-10 mM CaCl2.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Human Protein C purified from the supernatant of thrombin activated platelets.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PROC

Target: PROC (Vitamin K-dependent protein C (PROC))

Andere Bezeichnung: Protein C / PROC

Hintergrund: Protein C (PC) is a major physiological anticoagulant, and an important regulator of the blood coagulation system. PC is a vitamin K dependent serine protease enzyme that is activated by thrombin. The anticoagulant PC is converted to activated protein C (APC) by the thrombomodulin (TM) - thrombin complex on the phospholipid surface of endothelial cells, monocytes and platelets. APC degrades coagulation Factors Va and VIIIa rendering these factors inactive. APC provides physiologic antithrombotic activity and exhibits both anti-inflammatory and anti-apoptotic activity. Treatment with APC has been shown to improve the clinical outcome of patients with sepsis.Synonyms: Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Inactivator of coagulation factors Va and VIIIa, PROC1, Vitamin K-dependent protein C

Gen-ID: 5624

NCBI Accession: NP_000303

UniProt: P04070