Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
PON1
(Paraoxonase 1 (PON1))
Andere Bezeichnung
PON1
Hintergrund
The enzyme encoded by this gene is an Arylesterase that mainly hydrolyzes Paroxon to produce p-Nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.Synonyms: A-esterase 1, Aromatic esterase 1, EC=3.1.1.2, EC=3.1.8.1, K-45, PON, PON 1, PON-1, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1