PNMT Antikörper (N-Term)

Produktnummer ABIN954226

Dieser Maus Monoklonal Antikörper detektiert spezifisch PNMT in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PNMT Antikörper (N-Term) (ABIN954226)

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PNMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT1C11

Produktdetails anti-PNMT Antikörper

Bindungsspezifität: AA 1-282, N-Term

Spezifität: The antibody recognizes human PNMT. Other species not tested.

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human PNMT (1-282aa) purified from E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PNMT

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Andere Bezeichnung: PNMT / PENT

Hintergrund: Phenylethanolamine N-methyltransferase (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Expression of PNMT is regulated by hormonal and neural stimuli because its promoter contains sequences responding to cholinergic and depolarization stimuli. PNMT is the final enzyme in the catecholamine pathway, catalyzing the conversion of norepinephrine to epinephrine using as the cosubstrate and methyl donor, S-adenosylmethionine.Synonyms: Noradrenaline N-methyltransferase, PNMTase, Phenylethanolamine N-methyltransferase

Gen-ID: 5409

NCBI Accession: NP_002677

UniProt: P11086

Pathways: Response to Water Deprivation