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PF4 Antikörper

PF4 Reaktivität: Human WB, EIA Wirt: Maus Monoclonal RTO unconjugated
Produktnummer ABIN954175
  • Target Alle PF4 Antikörper anzeigen
    PF4 (Platelet Factor 4 (PF4))
    Reaktivität
    • 65
    • 14
    • 12
    • 1
    Human
    Wirt
    • 66
    • 17
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 69
    • 19
    Monoklonal
    Konjugat
    • 44
    • 15
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PF4 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 35
    • 34
    • 14
    • 11
    • 9
    • 9
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific for Human Platelet Factor IV. AM31850PU-N (clone RTO) is seen to bind free PF4 in the absence of any bound Heparin. This is unlike AM31851PU-N (clone KKO), which binds PF4/heparin complexes to a similar degree as auto-antibodies found in individuals with Heparin-Induced Thrombocytopenia/Thrombosis (HIT/HITT).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein G Chromatography of Ascitic fluid.
    Immunogen
    Human Factor IV purified from the supernatant of Thrombin activated platelets.
    Klon
    RTO
    Isotyp
    IgG2b
    Top Product
    Discover our top product PF4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PF4 (Platelet Factor 4 (PF4))
    Andere Bezeichnung
    Platelet Factor 4 / PF4 (PF4 Produkte)
    Synonyme
    CXCL4 antikoerper, PF-4 antikoerper, SCYB4 antikoerper, Cxcl4 antikoerper, Scyb4 antikoerper, Pf4a antikoerper, RATPF4A antikoerper, PF4A antikoerper, CXCL4L1 antikoerper, CXCL4V1 antikoerper, PF4-ALT antikoerper, SCYB4V1 antikoerper, PF4 antikoerper, platelet factor 4 antikoerper, platelet factor 4 variant 1 antikoerper, PF4 antikoerper, Pf4 antikoerper, LOC703451 antikoerper, PF4V1 antikoerper, LOC100524373 antikoerper, LOC102181854 antikoerper, LOC100630489 antikoerper
    Hintergrund
    Platelet Factor IV (PF4) is a 70 aa protein released from the alpha granules of activated platelets. PF4 is synthesized by bone marrow megakaryocytes and stored in alpha granules as a non-covalent bound tetramer. Platelet factor IV binds with high affinity to heparin and plays a role in inflammation and wound repair. PF4 is a chemoattractant for neutrophils, monocytes and fibroblasts and has been reported to be an immunologic regulator that inhibits suppressor T-cell activity.Synonyms: C-X-C motif chemokine 4, CXCL4, Iroplact, Oncostatin-A, PF-4, SCYB4
    Gen-ID
    5196
    NCBI Accession
    NP_002610
    UniProt
    P02776
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