Plakophilin 2 Antikörper (C-Term)

Produktnummer ABIN954172

Produktdetails anti-Plakophilin 2 Antikörper

Target: Plakophilin 2 (PKP2)

Bindungsspezifität: AA 837-866, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plakophilin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human Plakophilin-2 (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 837-866 amino acids from the C-terminal region of Human Plakophilin-2 Genename: PKP2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Plakophilin 2

Target: Plakophilin 2 (PKP2)

Andere Bezeichnung: Plakophilin-2 (PKP2 Produkte)

Synonyme: ARVD9 antikoerper, 1200008D14Rik antikoerper, 1200012P04Rik antikoerper, AA516617 antikoerper, Pkp2l antikoerper, plakophilin 2 antikoerper, PKP2 antikoerper, Pkp2 antikoerper

Hintergrund: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.Synonyms: PKP2

Molekulargewicht: 97415 Da

Gen-ID: 5318

NCBI Accession: NP_004563

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion