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PNN Antikörper (Middle Region)

PNN Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN954147
  • Target Alle PNN Antikörper anzeigen
    PNN (Pinin, Desmosome Associated Protein (PNN))
    Bindungsspezifität
    • 10
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 216-248, Middle Region
    Reaktivität
    • 45
    • 23
    • 10
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 4
    Kaninchen
    Klonalität
    • 42
    • 3
    Polyklonal
    Konjugat
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PNN Antikörper ist unkonjugiert
    Applikation
    • 36
    • 25
    • 16
    • 15
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes Human Pinin / PNN (Center).
    Aufreinigung
    Affinitty Chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 216-248 amino acids from the Central region of human PNN.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PNN Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PNN (Pinin, Desmosome Associated Protein (PNN))
    Andere Bezeichnung
    Pinin / PNN (PNN Produkte)
    Synonyme
    DRS antikoerper, DRSP antikoerper, SDK3 antikoerper, memA antikoerper, wu:fb24d03 antikoerper, pnn antikoerper, MGC88923 antikoerper, PNN antikoerper, AU045199 antikoerper, D12Ertd512e antikoerper, CG8383 antikoerper, Dmel\\CG8383 antikoerper, dPnn antikoerper, pinin, desmosome associated protein antikoerper, pinin antikoerper, Pinin antikoerper, PNN antikoerper, Pnn antikoerper, pnn antikoerper, LOC100380709 antikoerper
    Hintergrund
    Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.Synonyms: 140 kDa nuclear and cell adhesion-related phosphoprotein, DRS, DRSP, Desmosome-associated protein, Domain-rich serine protein, MEMA, Nuclear protein SDK3
    Molekulargewicht
    81614 Da
    Gen-ID
    5411
    NCBI Accession
    NP_002678
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