PHOX2B Antikörper (Middle Region)
Kurzübersicht für PHOX2B Antikörper (Middle Region) (ABIN954128)
Target
Alle PHOX2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 111-138, Middle Region
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Spezifität
- This antibody recognizes PHOX2B (Center).
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
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Aufreinigung
- Affinity Chromatography on Protein A
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 111-138) of Human PHOX2B.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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Andere Bezeichnung
- PHOX2B
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Hintergrund
- The DNA-associated protein encoded by the PHOX2B gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.Synonyms: NBPhox, Neuroblastoma Phox, PHOX2B homeodomain protein, PMX2B, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B
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Gen-ID
- 8929
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NCBI Accession
- NP_003915
Target
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