PCDHA7 Antikörper (Middle Region)

Produktnummer ABIN954035

Der Kaninchen Polyklonal Anti-PCDHA7-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, PCDHA7 in Proben von Human zu detektieren.

Kurzübersicht für PCDHA7 Antikörper (Middle Region) (ABIN954035)

Target: PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PCDHA7 Antikörper

Bindungsspezifität: AA 279-308, Middle Region

Spezifität: This antibody detecs human PCDHA7 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a protein A column, followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 279-308 aa) of human PCDHA7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PCDHA7

Target: PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Andere Bezeichnung: PCDHA7

Hintergrund: The PCDHA7 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.Synonyms: CNRS4, PCDH-alpha-7, Protocadherin alpha-7

Gen-ID: 56141

NCBI Accession: NP_061733